Department of Immunology

Martin Prlic, Ph.D.

ASSOCIATE PROFESSOR, FRED HUTCHINSON CANCER CENTER
AFFILIATE ASSOCIATE PROFESSOR, IMMUNOLOGY

Dr. Prlic earned his PhD from the University of Minnesota in 2004. He is currently an Associate Member in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center. Dr. Prlic joined the University of Washington Department of Immunology as an Affiliate Associate Professor in 2018. Dr. Prlic is also affiliated with the UW Department of Global Health, as well as the Pathobiology and Molecular and Cellular Biology Programs.

CONTACT

Mail Stop: E5-110
Ph: 206.664.2216
Fax: 206.664.2209

RESEARCH AREAS

Cancer Immunology
Cancer Biology

LAB MEMBERS

Prlic Lab Members

LAB

Prlic Lab

PUBMED

Prlic on PubMed

RESEARCH

The Prlic Lab primarily studies T cell and innate-like T cell responses in mucosal tissues with a particular interest in understanding how these cells function in different inflammatory environments including infections and cancer.

By defining the functional plasticity and functional potential of T cells in health and a range of different disease states we aim to understand how we can manipulate these cells to our advantage. Our goal is to understand the molecular basis of cell activation and differentiation to learn how to manipulate the cells for therapeutic purposes and ultimately improve human health.

PUBLICATIONS

  1. Mair F, Erickson JR, Frutoso M, Konecny AJ, Greene E, Voillet V, Maurice NJ, Rongvaux A, Dixon D, Barber B, Gottardo R and Prlic M. Extricating human tumour immune alterations from non-malignant tissue inflammation. Nature, 2022 May;605(7911):728-735. [PMID: 35545675]
  2. Erickson JR, Stevens-Ayers T, Mair F, Edmison B, Boeckh M, Bradley P, Prlic M. Convergent clonal selection of donor-and recipient-derived CMV-specific T cells in hematopoietic stem cell transplant patients Proc Natl Acad Sci, 2022 Feb 8;119(6):e2117031119. [PMID: 35105810]
  3. Woodward Davis AS, Slichter CK, Oberbillig H, Mair F, Erickson J, Lwo Y, Ko A, Dufort M, DeBerg H, Delany M, Linsley P, Dixon D, Darveau RP, Prlic M. The human tissue-resident CCR5+ T cell compartment maintains protective and regulatory properties during inflammation Sci Transl Med. 2019 Dec 4;11(521) [PMID: 31801887]
  4. Maurice NJ, McElrath MJ, Andersen-Nissen E, Frahm N, Prlic M. CXCR3 enables recruitment and site-specific bystander-activation of memory T cells. Nat Commun. 2019 Nov 1;10(1):4987. doi: 10.1038/s41467-019-12980-2. [PMID: 31676770]